Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs

Viral suppressors of RNA silencing (VSRSs) are a diverse group of viral proteins that have evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral pathogenicity. The p19 protein is a VSRS that selectively binds to short interfering RNAs (siRNAs) over microRNAs (miRNAs). M...

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Bibliographic Details
Main Authors: Dana V. Foss, Nicole T. Schirle, Ian J. MacRae, John Paul Pezacki
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12644