Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer

Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer

<p>Abstract</p> <p>Background</p> <p>Molecular and epidemiological evidence demonstrate that altered gene expression and single nucleotide polymorphisms in the apoptotic pathway are linked to many cancers. Yet, few studies emphasize the interaction of variant apoptotic...

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Bibliographic Details
Main Authors: Lavender Nicole A, Rogers Erica N, Yeyeodu Susan, Rudd James, Hu Ting, Zhang Jie, Brock Guy N, Kimbro Kevin S, Moore Jason H, Hein David W, Kidd La Creis R
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Medical Genomics
Subjects:
Prostate cancer
Apoptosis
Single nucleotide polymorphisms
Gene-gene interactions
Multifactor dimensionality reduction (MDR)
Statistical epistasis networks (SEN)
Online Access:http://www.biomedcentral.com/1755-8794/5/11

Internet

http://www.biomedcentral.com/1755-8794/5/11

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