Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis

Lymph nodes (LNs) are a common site of metastasis in solid cancers, and cutaneous melanomas show inherent properties of LN colonization. However, interactions between LN stroma and pioneer metastatic cells during metastatic colonization remain largely uncharacterized. Here we studied mice implanted...

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Bibliographic Details
Main Authors: Rohit Singh, Beom K Choi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48916