Allergy-associated T cell epitope repertoires are surprisingly diverse and include non-IgE reactive antigens

We recently identified T cell epitopes associated with human allergic responses. In a majority of cases, responses focused on a few immunodominant epitopes which can be predicted on the basis of MHC binding characteristics. Several observations from our studies challenged the assumption that T cell...

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Bibliographic Details
Main Authors: April Frazier, Veronique Schulten, Denise Hinz, Carla Oseroff, John Sidney, Bjoern Peters, Alessandro Sette
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119302558