Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.

Kinesin-8 proteins are microtubule motors that are often involved in regulation of mitotic spindle length and chromosome alignment. They move towards the plus ends of spindle microtubules and regulate the dynamics of these ends due, at least in some species, to their microtubule depolymerization act...

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Bibliographic Details
Main Authors: Mohammad Zeeshan, Fiona Shilliday, Tianyang Liu, Steven Abel, Tobias Mourier, David J P Ferguson, Edward Rea, Rebecca R Stanway, Magali Roques, Desiree Williams, Emilie Daniel, Declan Brady, Anthony J Roberts, Anthony A Holder, Arnab Pain, Karine G Le Roch, Carolyn A Moores, Rita Tewari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008048