Neuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage

<p>Abstract</p> <p>Background</p> <p>Glutamate-mediated excitotoxicity, primarily through N-methyl-D-aspartate (NMDA) receptors, may be an important cause of retinal ganglion cells (RGCs) death in glaucoma and several other retinal diseases. Bis(7)-tacrine is a noncompe...

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Bibliographic Details
Main Authors: Xu Zhi, Wang Xing, Fang Jia, Jiang Fa
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/31