Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

A series of novel quaternary ammonium 4-deoxypyridoxine derivatives was synthesized. Two compounds demonstrated excellent activity against a panel of Gram-positive methicillin-resistant S. aureus strains with MICs in the range of 0.5–2 μg/mL, exceeding the activity of miramistin. At the same time, b...

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Bibliographic Details
Main Authors: Nikita V. Shtyrlin, Sergey V. Sapozhnikov, Albina S. Galiullina, Airat R. Kayumov, Oksana V. Bondar, Elena P. Mirchink, Elena B. Isakova, Alexander A. Firsov, Konstantin V. Balakin, Yurii G. Shtyrlin
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3864193

Internet

http://dx.doi.org/10.1155/2016/3864193

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