Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice

Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice

Background: Hepatocyte growth factor (HGF) is a multifunctional growth factor that promotes various biological processes. However, the effect of HGF on bone metabolism in rheumatoid arthritis (RA) remains unknown. Here, we investigated the role of HGF in regulating osteoclastogenesis and bone resorp...

Full description

Bibliographic Details
Main Authors: Chaoming Huang, Yufan Zheng, Jinyu Bai, Ce Shi, Xin Shi, Huajian Shan, Xiaozhong Zhou
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Orthopaedic Translation
Subjects:
HGF
Osteoclast
Rheumatoid arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X20301248

Internet

http://www.sciencedirect.com/science/article/pii/S2214031X20301248

Similar Items