The Use of Myelinating Cultures as a Screen of Glycomolecules for CNS Repair

In vitro cell-based assays have been fundamental in modern drug discovery and have led to the identification of novel therapeutics. We have developed complex mixed central nervous system (CNS) cultures, which recapitulate the normal process of myelination over time and allow the study of several par...

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Bibliographic Details
Main Authors: George A. McCanney, Susan L. Lindsay, Michael A. McGrath, Hugh J. Willison, Claire Moss, Charles Bavington, Susan C. Barnett
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/8/3/52