Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors.

The myelodysplastic syndromes (MDS) comprise a heterogeneous group of malignant neoplasms with distinctive clinicopathological features. Currently, there is no specific approach for the treatment of MDS. Here, we report that bortezomib (BTZ), a proteasome inhibitor that has been used to treat plasma...

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Bibliographic Details
Main Authors: Yingxing Yue, Ying Wang, Yang He, Shuting Yang, Zixing Chen, Yuanyuan Wang, Shanshan Xing, Congcong Shen, Hesham M Amin, Depei Wu, Yao-Hua Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946707?pdf=render