The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy

The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy

Several chronic neuroinflammatory diseases, including Parkinson’s disease (PD), have the so-called ‘redox imbalance’ in common, a dynamic system modulated by various factors. Among them, alteration of the mitochondrial functionality can cause overproduction of reactive oxygen species (ROS) with the...

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Bibliographic Details
Main Authors: Sara Travaglione, Stefano Loizzo, Rosa Vona, Giulia Ballan, Roberto Rivabene, Danila Giordani, Marco Guidotti, Maria Luisa Dupuis, Zaira Maroccia, Monica Baiula, Roberto Rimondini, Gabriele Campana, Carla Fiorentini
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
6-hydroxydopamine
mitochondria
cytotoxic necrotizing factor type 1
oxidative stress
reactive oxygen species
macroautophagy
Online Access:https://www.mdpi.com/1422-0067/21/9/3390

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https://www.mdpi.com/1422-0067/21/9/3390

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