New Thiosemicarbazides and 1,2,4-Triazolethiones Derived from 2-(Ethylsulfanyl) Benzohydrazide as Potent Antioxidants

New Thiosemicarbazides and 1,2,4-Triazolethiones Derived from 2-(Ethylsulfanyl) Benzohydrazide as Potent Antioxidants

New thiosemicarbazide derivatives 2–6 were synthesised by reacting 2-(ethylsulfanyl)benzohydrazide with various aryl isothiocyanates. The cyclisation of compounds 2–6 under reflux conditions in a basic medium (aqueous NaOH, 4 N) yielded compounds 7–11 that contain a 1,2,4-triazole ring. All of the...

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Bibliographic Details
Main Authors: Nafal Nazarbahjat, Nurdiana Nordin, Zanariah Abdullah, Mahmood Ameen Abdulla, Wageeh A. Yehye, Siti Nadiah Abdul Halim, Chin Hui Kee, Azhar Ariffin
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
thiosemicarbazide derivatives
1,2,4-triazoles
thioethers
X-ray structure determination
antioxidant activity
Online Access:http://www.mdpi.com/1420-3049/19/8/11520

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http://www.mdpi.com/1420-3049/19/8/11520

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