Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential

Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential

<p>Abstract</p> <p>Background</p> <p>Like all mammalian cells, normal adult chondrocytes have a limited replicative life span, which decreases with age. To facilitate the therapeutic use of chondrocytes from older donors, a method is needed to prolong their life span.&l...

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Bibliographic Details
Main Authors: Sato Masato, Shin-ya Kazuo, Lee Jeong Ik, Ishihara Miya, Nagai Toshihiro, Kaneshiro Nagatoshi, Mitani Genya, Tahara Hidetoshi, Mochida Joji
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/13/51

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