Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential
<p>Abstract</p> <p>Background</p> <p>Like all mammalian cells, normal adult chondrocytes have a limited replicative life span, which decreases with age. To facilitate the therapeutic use of chondrocytes from older donors, a method is needed to prolong their life span.&l...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-04-01
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Series: | BMC Musculoskeletal Disorders |
Online Access: | http://www.biomedcentral.com/1471-2474/13/51 |