Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases

Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases

Monocytes are crucial regulators of inflammation, and are characterized by three distinct subsets in humans, of which classical and non-classical are the most abundant. Different subsets carry out different functions and have been previously associated with multiple inflammatory conditions. Dissecti...

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Bibliographic Details
Main Authors: Francesco Vallania, Liron Zisman, Claudia Macaubas, Shu-Chen Hung, Narendiran Rajasekaran, Sonia Mason, Jonathan Graf, Mary Nakamura, Elizabeth D. Mellins, Purvesh Khatri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Systems Immunology
Gene signatures
monocyte subsets
gene expression
flow cytometry markers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.659255/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.659255/full

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