Rituximab prevents and reverses cardiac remodeling by depressing B cell function in mice

B lymphocytes have been shown to contribute to autoimmune diseases via producing antibodies and proinflammatory cytokines. Depletion of B cells by blocking CD20 can inhibit these diseases. Here we examined whether an antibody against CD20, rituximab (RTX) (Rituxan@), used clinically in oncology coul...

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Bibliographic Details
Main Authors: Xiao-Lei Ma, Qiu-Yue Lin, Lei Wang, Xin Xie, Yun-Long Zhang, Hui-Hua Li
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219301635