Yeast-based assays for the functional characterization of cancer-associated variants of human DNA repair genes

Technological advances are continuously revealing new genetic variants that are often difficult to interpret. As one of the most genetically tractable model organisms, yeast can have a central role in determining the consequences of human genetic variation. DNA repair gene mutations are associated w...

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Bibliographic Details
Main Authors: Tiziana Cervelli, Samuele Lodovichi, Francesca Bellè, Alvaro Galli
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-05-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/2020a-cervelli-microbial-cell/