A PRELIMINARY STUDY OF STEREOSELECTIVITY OF MEFLOQUINE ENANTIOMERS IN RAT
Stereoselectivity of mefloquine enantiomers were studied in rats after oral administration of a single 50mg/Kg dose of the racemate. Pharmacokinetic parameters of (+)-(RS)-MFQ in blood and plasma showed no significant difference. The concentration, AUC , CLIF and VdlF of (+)-(RS)-enantiomerin blood...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
1998-08-01
|
| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4887.pdf&manuscript_id=4887 |