Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.

The three sub-species of Trypanosoma brucei are important pathogens of sub-Saharan Africa. T. b. brucei is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. T. b. rhodesiense and T. b. gambiense are able to resist lysis by TLF. There are two...

Full description

Bibliographic Details
Main Authors: Paul Capewell, Nicola J Veitch, C Michael R Turner, Jayne Raper, Matthew Berriman, Stephen L Hajduk, Annette MacLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3167774?pdf=render