Depigmented Allergoids Reveal New Epitopes with Capacity to Induce IgG Blocking Antibodies

Background. The synthesis of allergen-specific blocking IgGs that interact with IgE after allergen immunotherapy (SIT) has been related to clinical efficacy. The objectives were to investigate the epitope specificity of IgG-antibodies induced by depigmented-polymerized (Dpg-Pol) allergoids and unmod...

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Bibliographic Details
Main Authors: M. Angeles López-Matas, Mayte Gallego, Víctor Iraola, Douglas Robinson, Jerónimo Carnés
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/284615