Blood Compatibility—An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application

Blood Compatibility—An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application

Acylation of antimicrobial peptides mimics the structure of the natural lipopeptide polymyxin B, and increases antimicrobial and endotoxin-neutralizing activities. In this study, the antimicrobial properties of lactoferrin-based LF11 peptides as well as blood compatibility as a function of acyl chai...

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Bibliographic Details
Main Authors: Stephan Harm, Karl Lohner, Ute Fichtinger, Claudia Schildböck, Jennifer Zottl, Jens Hartmann
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial peptides
inflammation
sepsis
endotoxin
blood compatibility
Online Access:https://www.mdpi.com/1422-0067/20/21/5426

Internet

https://www.mdpi.com/1422-0067/20/21/5426

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