Relationship Between Herpes Simplex Virus-1-Specific Antibody Titers and cortical brain damage in Alzheimer's Disease and amnestic Mild Cognitive Impairment

Relationship Between Herpes Simplex Virus-1-Specific Antibody Titers and cortical brain damage in Alzheimer's Disease and amnestic Mild Cognitive Impairment

Alzheimer’s disease (AD) is a multifactorial disease with a still barely understood etiology. Herpes simplex virus 1 (HSV-1) has long been suspected to play a role in the pathogenesis of AD because of its neurotropism, high rate of infection in the general population, and life-long persistence in ne...

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Bibliographic Details
Main Authors: Roberta eMancuso, Francesca eBaglio, Simone eAgostini, Monia eCabinio, Maria Marcella Laganà, Ambra eHernis, Nicolo eMargaritella, Franca Rosa Guerini, Milena eZanzottera, Raffaello eNemni, Mario eClerici
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
HSV-1
Alzheimer’s disease (AD)
magnetic resonance imaging (MRI)
amnestic mild cognitive impairment (aMCI)
Voxel Based Morphometry (VBM)
HSV-1 IgG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00285/full

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http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00285/full

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