The impact of the IGF-1 system of cancer cells on radiation response â An in vitro study
Background: Overexpression of the insulin-like growth factor-1 receptor (IGF-1R) is associated with increased cell proliferation, differentiation, transformation, and tumorigenicity. Additionally, signaling involved in the resistance of cancer cells to radiotherapy originates from IGF-1R. The purpos...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-12-01
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Series: | Clinical and Translational Radiation Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405630817300253 |