RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.

Characteristic hypoglycemia, hypotriglyceridemia, hypocholesterolemia, lower body mass, and fat as well as pronounced insulin-sensitivity of RLIP76⁻/⁻ mice suggested to us the possibility that elevation of RLIP76 in response to stress could itself elicit metabolic syndrome (MSy). Indeed, if it were...

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Bibliographic Details
Main Authors: Jyotsana Singhal, Lokesh Nagaprashantha, Rit Vatsyayan, Sanjay Awasthi, Sharad S Singhal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3172288?pdf=render