Counterfeit and Substandard Test of the Antimalarial Tablet Riamet<sup>®</sup> by Means of Raman Hyperspectral Multicomponent Analysis

Counterfeit and Substandard Test of the Antimalarial Tablet Riamet<sup>®</sup> by Means of Raman Hyperspectral Multicomponent Analysis

The fight against counterfeit pharmaceuticals is a global issue of utmost importance, as failed medication results in millions of deaths every year. Particularly affected are antimalarial tablets. A very important issue is the identification of substandard tablets that do not contain the nominal amo...

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Bibliographic Details
Main Authors: Timea Frosch, Elisabeth Wyrwich, Di Yan, Christian Domes, Robert Domes, Juergen Popp, Torsten Frosch
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
Raman spectroscopy
hyperspectral imaging
analytical spectroscopy
counterfeit and substandard pharmaceuticals
DFT calculations
chemometrics
PLSR
API
lumefantrine
artemether
antimalarial tablets
Online Access:https://www.mdpi.com/1420-3049/24/18/3229

Internet

https://www.mdpi.com/1420-3049/24/18/3229

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