Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection.

Enteropathogenic bacteria are a frequent cause of diarrhea worldwide. The mucosal defenses against infection are not completely understood. We have used the streptomycin mouse model for Salmonella Typhimurium diarrhea to analyze the role of interferon gamma receptor (IFN-γR)-signaling in mucosal def...

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Bibliographic Details
Main Authors: Pascal Songhet, Manja Barthel, Bärbel Stecher, Andreas J Müller, Marcus Kremer, Gunnar C Hansson, Wolf-Dietrich Hardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3145644?pdf=render