Advances in Patient-Specific Induced Pluripotent Stem Cells Shed Light on Drug Discovery for Amyotrophic Lateral Sclerosis

Induced pluripotent stem cells (iPSCs), which are generated through reprogramming adult somatic cells by expressing specific transcription factors, can differentiate into derivatives of the three embryonic germ layers and accelerate rapid advances in stem cell research. Neurological diseases such as...

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Bibliographic Details
Main Authors: Jui-Hao Lee, Jen-Wei Liu, Shinn-Zong Lin, Horng-Jyh Harn, Tzyy-Wen Chiou
Format: Article
Language:English
Published: SAGE Publishing 2018-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718785154