Novel treatment strategies in triple-negative breast cancer: specific role of poly(adenosine diphosphate-ribose) polymerase inhibition
M William Audeh Division of Medical Oncology, Samuel Oschin Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA Abstract: Inhibitors of the poly(adenosine triphosphate-ribose) polymerase (PARP)-1 enzyme induce synthetic lethality in cancers with ineffective DNA (DNA) repair or homo...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2014-10-01
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| Series: | Pharmacogenomics and Personalized Medicine |
| Online Access: | http://www.dovepress.com/novel-treatment-strategies-in-triple-negative-breast-cancer-specific-r-peer-reviewed-article-PGPM |