Tau and neurodegenerative disorders

The mechanisms that render tau a toxic agent are still unclear, although increasing evidence supports the assertion that alterations of tau can directly cause neuronal degeneration. In addition, it is unclear whether neurodegeneration in various tauopathies occurs via a common mechanism or that spec...

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Bibliographic Details
Main Authors: Motoi Yumiko, Sahara Naruhiko, Kambe Taiki, Hattori Nobutaka
Format: Article
Language:English
Published: De Gruyter 2010-08-01
Series:Biomolecular Concepts
Subjects:
tau
Online Access:https://doi.org/10.1515/bmc.2010.017