Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus

Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus

Profound astrogliosis coincident with neuronal cell loss is universally described in human and animal models of temporal lobe epilepsy (TLE). In the kainic acid-induced status epilepticus (SE) model of TLE, astrocytes in the hippocampus become reactive soon after SE and before the onset of spontaneo...

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Bibliographic Details
Main Authors: D.K. Takahashi, J.R. Vargas, K.S. Wilcox
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
Temporal lobe epilepsy
Gap junction
Glutamate transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110002524

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http://www.sciencedirect.com/science/article/pii/S0969996110002524

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