Preeclampsia serum upregulates CD40/CD40L expression and induces apoptosis in human umbilical cord endothelial cells

Preeclampsia serum upregulates CD40/CD40L expression and induces apoptosis in human umbilical cord endothelial cells

<p>Abstract</p> <p>Background</p> <p>The endothelial cell dysfunction observed in preeclampsia (PE) may be induced by CD40/CD40L signaling. This study investigated the role of CD40/CD40L in the pathogenesis of PE by comparing the effect of maternal serum obtained from h...

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Bibliographic Details
Main Authors: Wu Chun-feng, Huang Fu-dan, Sui Ren-fang, Sun Jing-xia
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Reproductive Biology and Endocrinology
Subjects:
Preeclampsia
Endothelial dysfunction
CD40/CD40L
Human umbilical cord endothelial cells
Online Access:http://www.rbej.com/content/10/1/28

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http://www.rbej.com/content/10/1/28

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