Risk factors for losing hepatitis B virus surface antibody in patients with HBV surface antigen negative/surface antibody positive serostatus receiving biologic disease-modifying anti-rheumatic drugs: a nested case-control study

Abstract Background Hepatitis B virus (HBV) reactivation consequent to immunosuppressive therapy is an increasingly prevalent problem with serious clinical implications. Treatment with biologic agents conduces to the loss of protective antibody to HBV surface antigen (anti-HBs), which significantly...

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Bibliographic Details
Main Authors: Ming-Hui Hung, Ya-Chih Tien, Ying-Ming Chiu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Advances in Rheumatology
Subjects:
Online Access:https://doi.org/10.1186/s42358-021-00173-9