Risk factors for losing hepatitis B virus surface antibody in patients with HBV surface antigen negative/surface antibody positive serostatus receiving biologic disease-modifying anti-rheumatic drugs: a nested case-control study
Abstract Background Hepatitis B virus (HBV) reactivation consequent to immunosuppressive therapy is an increasingly prevalent problem with serious clinical implications. Treatment with biologic agents conduces to the loss of protective antibody to HBV surface antigen (anti-HBs), which significantly...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | Advances in Rheumatology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s42358-021-00173-9 |