Comprehensive small animal imaging strategies on a clinical 3 T dedicated head MR-scanner; adapted methods and sequence protocols in CNS pathologies.

<h4>Background</h4>Small animal models of human diseases are an indispensable aspect of pre-clinical research. Being dynamic, most pathologies demand extensive longitudinal monitoring to understand disease mechanisms, drug efficacy and side effects. These considerations often demand the...

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Main Authors: Deepu R Pillai, Robin M Heidemann, Praveen Kumar, Nagesh Shanbhag, Titus Lanz, Michael S Dittmar, Beatrice Sandner, Christoph P Beier, Norbert Weidner, Mark W Greenlee, Gerhard Schuierer, Ulrich Bogdahn, Felix Schlachetzki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21326876/pdf/?tool=EBI