Characterization of a pathogenic variant in GBA for Parkinson’s disease with mild cognitive impairment patients

Characterization of a pathogenic variant in GBA for Parkinson’s disease with mild cognitive impairment patients

Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease, and mild cognitive impairment (MCI) is a well-established risk factor for the development of dementia in PD. A growing body of evidence suggests that low expression of glucocerebrosidase (GBA) promotes the transmi...

Full description

Bibliographic Details
Main Authors: Zhiqiang Jiang, Yilin Huang, Piao Zhang, Chongyin Han, Yueer Lu, Zongchao Mo, Zhanyu Zhang, Xin Li, Sisi Zhao, Fuqiang Cai, Lizhen Huang, Chunbo Chen, Zhihong Shi, Yuhu Zhang, Fei Ling
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Molecular Brain
Subjects:
GBA
rs12411216
α-Synuclein
Parkinson’s disease-mild cognitive impairment
Online Access:http://link.springer.com/article/10.1186/s13041-020-00637-x

Internet

http://link.springer.com/article/10.1186/s13041-020-00637-x

Similar Items