Ischemic Postconditioning-Mediated DJ-1 Activation Mitigate Intestinal Mucosa Injury Induced by Myocardial Ischemia Reperfusion in Rats Through Keap1/Nrf2 Pathway

Ischemic Postconditioning-Mediated DJ-1 Activation Mitigate Intestinal Mucosa Injury Induced by Myocardial Ischemia Reperfusion in Rats Through Keap1/Nrf2 Pathway

Intestinal mucosal barrier dysfunction induced by myocardial ischemia reperfusion (IR) injury often leads to adverse cardiovascular outcomes after myocardial infarction. Early detection and prevention of remote intestinal injury following myocardial IR may help to estimate and improve prognosis afte...

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Bibliographic Details
Main Authors: Rong Chen, Wei Li, Zhen Qiu, Qin Zhou, Yuan Zhang, Wen-yuan Li, Ke Ding, Qing-tao Meng, Zhong-yuan Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
intestinal barrier injury
ischemic postconditioning
DJ-1
myocardial ischemia reperfusion
nuclear factor (erythroid-derived 2)-like 2
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.655619/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.655619/full

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