A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset

A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset

A decrease in the fraction of non-classical monocytes is a hallmark of chronic myelomonocytic leukaemia. Taking advantage of this abnormal situation, the authors identify a mechanistic link between miR-150 and TET3 as being involved in monocyte subset generation.

Bibliographic Details
Main Authors: Dorothée Selimoglu-Buet, Julie Rivière, Hussein Ghamlouch, Laura Bencheikh, Catherine Lacout, Margot Morabito, M’boyba Diop, Guillaume Meurice, Marie Breckler, Aurélie Chauveau, Camille Debord, Franck Debeurme, Raphael Itzykson, Nicolas Chapuis, Christophe Willekens, Orianne Wagner-Ballon, Olivier A. Bernard, Nathalie Droin, Eric Solary
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07801-x

Internet

https://doi.org/10.1038/s41467-018-07801-x

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