Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema

Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema

Macrophages play a pivotal role in the development of emphysema and depending on the microenvironment stimuli can be polarized into M1- or M2-like macrophage phenotypes. We compared macrophage polarizations in cigarette smoke (CS)- and porcine pancreatic elastase (PPE)-induced emphysema models. C57B...

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Bibliographic Details
Main Authors: Júlia Benini Kohler, Daniela Aparecida de Brito Cervilha, Alyne Riani Moreira, Fernanda Roncon Santana, Talita M. Farias, Maria Isabel Cardoso Alonso Vale, Milton de Arruda Martins, Carla Máximo Prado, Iolanda Calvo Tibério, Juliana Tiyaki Ito, Fernanda Degobbi Tenorio Quirino dos Santos Lopes
Format: Article
Language:English
Published: The Company of Biologists 2019-04-01
Series:Biology Open
Subjects:
Macrophages polarization
M1-like phenotypes
M2-like phenotypes
Pulmonary emphysema
Animal model
Online Access:http://bio.biologists.org/content/8/4/bio040808

Internet

http://bio.biologists.org/content/8/4/bio040808

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