KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

The KH-type splicing regulatory protein (KSRP) promotes the decay of AU-rich element (ARE)-containing mRNAs. Although KSRP is expressed in the nervous system, very little is known about its role in neurons. In this study, we examined whether KSRP regulates the stability of the ARE-containing GAP-43...

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Bibliographic Details
Main Authors: Clark W Bird, Amy S Gardiner, Federico Bolognani, Daniel C Tanner, Ching-Yi Chen, Wei-Jye Lin, Soonmoon Yoo, Jeffery L Twiss, Nora Perrone-Bizzozero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828348?pdf=render

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http://europepmc.org/articles/PMC3828348?pdf=render

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