Visualization of network target crosstalk optimizes drug synergism in myocardial ischemia.
Numerous drugs and compounds have been validated as protecting against myocardial ischemia (MI), a leading cause of heart failure; however, synergistic possibilities among them have not been systematically explored. Thus, there appears to be significant room for optimization in the field of drug com...
Main Authors: | Xiaojing Wan, Jia Meng, Yingnan Dai, Yina Zhang, Shuang Yan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3914923?pdf=render |
Similar Items
-
Paeonol Protects Against Myocardial Ischemia/Reperfusion-Induced Injury by Mediating Apoptosis and Autophagy Crosstalk
by: Chin-Feng Tsai, et al.
Published: (2021-01-01) -
Crosstalk Between Autophagy and Cerebral Ischemia
by: Yulin Sun, et al.
Published: (2019-01-01) -
Comparative study on the morphology, chemistry, metabolism and anti-myocardial ischemia activity of three medicinal species of dioscorea
by: Tang, Yina
Published: (2015) -
Synergic Crosstalk between Inflammation, Oxidative Stress, and Genomic Alterations in BCR–ABL-Negative Myeloproliferative Neoplasm
by: Alessandro Allegra, et al.
Published: (2020-10-01) -
Redox-Related Neuronal Death and Crosstalk as Drug Targets: Focus on Epilepsy
by: Xiao-Yuan Mao, et al.
Published: (2019-05-01)