Visualization of network target crosstalk optimizes drug synergism in myocardial ischemia.

Numerous drugs and compounds have been validated as protecting against myocardial ischemia (MI), a leading cause of heart failure; however, synergistic possibilities among them have not been systematically explored. Thus, there appears to be significant room for optimization in the field of drug com...

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Bibliographic Details
Main Authors: Xiaojing Wan, Jia Meng, Yingnan Dai, Yina Zhang, Shuang Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914923?pdf=render