The Fate of Speckled Protein 100 (Sp100) During Herpesviruses Infection
The constitutive expression of Speckled-100 (Sp100) is known to restrict the replication of many clinically important DNA viruses. This pre-existing (intrinsic) immune defense to virus infection can be further upregulated upon interferon (IFN) stimulation as a component of the innate immune response...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2021-02-01
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Series: | Frontiers in Cellular and Infection Microbiology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2020.607526/full |