Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

Abstract Genetic factors contribute to the development of autism spectrum disorder (ASD), and although non-protein-coding regions of the genome are being increasingly implicated in ASD, the functional consequences of these variants remain largely uncharacterized. Induced pluripotent stem cells (iPSC...

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Bibliographic Details
Main Authors: P. Joel Ross, Rebecca S. F. Mok, Brandon S. Smith, Deivid C. Rodrigues, Marat Mufteev, Stephen W. Scherer, James Ellis
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Autism
Online Access:http://link.springer.com/article/10.1186/s13229-020-00333-6

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http://link.springer.com/article/10.1186/s13229-020-00333-6

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