Neutralizing Antibody Response and Efficacy of Novel Recombinant Tetravalent Dengue DNA Vaccine Comprising Envelope Domain III in Mice

Background: Dengue is a global arboviral threat to humans; causing 390 million infections per year. The availability of safe and effective tetravalent dengue vaccine is a global requirement to prevent epidemics, morbidity, and mortality associated with it. Methods: Five experimental groups (6 mice...

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Bibliographic Details
Main Authors: Ajit Kulkarni, Rushil Bhat, Mansi Malik, Suvarna Sane, Sweta Kothari, Shashikant Vaidya, Abhay Chowdhary, Ranjana A. Deshmukh
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-03-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/2506