Antibiotic-Induced Pathobiont Dissemination Accelerates Mortality in Severe Experimental Pancreatitis

Antibiotic-Induced Pathobiont Dissemination Accelerates Mortality in Severe Experimental Pancreatitis

Although antibiotic-induced dysbiosis has been demonstrated to exacerbate intestinal inflammation, it has been suggested that antibiotic prophylaxis may be beneficial in certain clinical conditions such as acute pancreatitis (AP). However, whether broad-spectrum antibiotics, such as meropenem, influ...

Full description

Bibliographic Details
Main Authors: Fernanda S. Soares, Flávia C. Amaral, Natália L. C. Silva, Matheus R. Valente, Lorena K. R. Santos, Lívia H. Yamashiro, Mara C. Scheffer, Fernanda V. E. S. Castanheira, Raphael G. Ferreira, Laura Gehrke, José C. Alves-Filho, Luciano P. Silva, André Báfica, Fernando Spiller
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
experimental acute pancreatitis
meropenem-induced pathobiont
Enterococcus gallinarum
microbiota
sepsis
antibiotics
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01890/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01890/full

Similar Items