P2O5/SiO2 as an Efficient, Green and Heterogeneous Catalytic System for the Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2-(1H)-ones (and -Thiones)

A simple, green and efficient solventless procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (and -thiones) from aldehydes, β-ketoesters and urea or thiourea in the presence of catalytic amount of silica-supported P2O5 (P2O5/SiO2) at 85 °C is described. Using this method, the title comp...

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Bibliographic Details
Main Authors: Alireza Hasaninejad, Abdolkarim Zare, Farhad Jafari, Ahmad Reza Moosavi-Zare
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/303781