Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.

Characterization of an isotype-dependent monoclonal antibody against linear neutralizing epitope effective for prophylaxis of enterovirus 71 infection.

BACKGROUND: Enterovirus 71 (EV71) is the main causative agent of Hand, Foot and Mouth disease (HFMD) and is associated with severe neurologic complications and mortalities. At present, there is no vaccine or therapeutic available for treatment. METHODOLOGY/PRINCIPAL FINDING: In this study, we genera...

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Bibliographic Details
Main Authors: Xiao Fang Lim, Qiang Jia, Wei Xin Khong, Benedict Yan, Balraj Premanand, Sylvie Alonso, Vincent T K Chow, Jimmy Kwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3261156?pdf=render

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http://europepmc.org/articles/PMC3261156?pdf=render

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