B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain.

The B(0)AT2 protein is a product of the SLC6A15 gene belonging to the SLC6 subfamily and has been shown to be a transporter of essential branched-chain amino acids. We aimed to further characterize the B(0)AT2 transporter in CNS, and to use Slc6a15 knock out (KO) mice to investigate whether B(0)AT2...

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Bibliographic Details
Main Authors: Maria G A Hägglund, Sahar Roshanbin, Erik Löfqvist, Sofie V Hellsten, Victor C O Nilsson, Aniruddha Todkar, Yinan Zhu, Olga Stephansson, Jana Drgonova, George R Uhl, Helgi B Schiöth, Robert Fredriksson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3591439?pdf=render