Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice.

There is increasing evidence that unacylated ghrelin (UAG) improves insulin sensitivity and glucose homeostasis; however, the mechanism for this activity is not fully understood since a UAG receptor has not been discovered.To assess potential mechanisms of UAG action in vivo, we examined rapid effec...

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Bibliographic Details
Main Authors: Patric J D Delhanty, Yuxiang Sun, Jenny A Visser, Anke van Kerkwijk, Martin Huisman, Wilfred F J van Ijcken, Sigrid Swagemakers, Roy G Smith, Axel P N Themmen, Aart-Jan van der Lely
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909919?pdf=render