Comorbidity of Pain and Depression in a Lumbar Disc Herniation Model: Biochemical Alterations and the Effects of Fluoxetine

Comorbidity of Pain and Depression in a Lumbar Disc Herniation Model: Biochemical Alterations and the Effects of Fluoxetine

Summary of Background Data: Depression is one of the most common comorbidities in patients with chronic low back pain. However, the mechanisms of depression in chronic low back pain patients and the effect of antidepressants on the comorbidity of pain and depression need to be further explored. The...

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Bibliographic Details
Main Authors: Lun Cai, Qianchao He, Yongjing Lu, Yuying Hu, Wei Chen, Liping Wei, Yueqiang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neurology
Subjects:
lumbar disc herniation
mechanical allodynia
thermal hyperalgesia
depression
serotonin
TNF-α
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01022/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.01022/full

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