Regulation of glycolysis in brown adipocytes by HIF-1α

Abstract Brown adipose tissue takes up large amounts of glucose during cold exposure in mice and humans. Here we report an induction of glucose transporter 1 expression and increased expression of several glycolytic enzymes in brown adipose tissue from cold-exposed mice. Accordingly, these genes wer...

Full description

Bibliographic Details
Main Authors: Astrid L. Basse, Marie S. Isidor, Sally Winther, Nina B. Skjoldborg, Maria Murholm, Elise S. Andersen, Steen B. Pedersen, Christian Wolfrum, Bjørn Quistorff, Jacob B. Hansen
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04246-y